5-(3,4-Dichlorobenzyl-carbamoyl)-thiophene-2-carboxylic acid ethyl ester → 5(3,4-Dichlorobenzylcarbamoyl)-pyridine-2-carboxylic acid

HRID 144087Notes

Reaction equation

HRID 144087 reaction equation
[CH2:23]([O:24][C:25]([c:26]1[s:27][c:28]([C:29](=[O:30])[NH:31][CH2:32][c:33]2[cH:34][cH:35][c:36]([Cl:37])[c:38]([Cl:39])[cH:40]2)[cH:41][cH:42]1)=[O:43])[CH3:44].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][cH:7][c:8]([C:11]([NH:12][CH2:13][c:14]2[cH:15][c:16]([Cl:21])[c:17]([Cl:20])[cH:18][cH:19]2)=[O:22])[cH:9][cH:10]1>>[O:2]=[C:3]([OH:4])[c:5]1[n:6][cH:7][c:8]([C:11]([NH:12][CH2:13][c:14]2[cH:15][c:16]([Cl:21])[c:17]([Cl:20])[cH:18][cH:19]2)=[O:22])[cH:9][cH:10]1

Participants

3

Reactant 2

HCID 229861535-(3,4-Dichlorobenzyl-carbamoyl)-thiophene-2-carboxylic acid ethyl esterHCID 229861925(3,4-Dichlorobenzylcarbamoyl)-pyridine-2-carboxylic acid methyl-ester

Product 1

HCID 186171845(3,4-Dichlorobenzylcarbamoyl)-pyridine-2-carboxylic acid

Sources & evidence

ORD record
ord-3c376a975d914caea0b5482be5ec1ef9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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