Toluene → 2-Butoxy-2-phenylethanal

HRID 1440876Notes

Reaction equation

HRID 1440876 reaction equation
C1(C(OCCC)CO)C=CC=CC=1.[CH2:14]([O:18][CH:19]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[CH2:20][OH:21])[CH2:15][CH2:16][CH3:17].C1(C)C=CC=CC=1>C1CCCCC1>[CH2:14]([O:18][CH:19]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[CH:20]=[O:21])[CH2:15][CH2:16][CH3:17]

Participants

5

Reactant 3

HCID 1140TolueneHCID 109868792-Phenyl-2-propoxyethanolHCID 143640482-Butoxy-2-phenylethanol

Product 1

HCID 189826062-Butoxy-2-phenylethanalYield 68%

Reagents, catalysts & solvents 1

HCID 8078CyclohexaneSolvent

Procedure

The procedure in Example 3 was repeated except that 180.25 g of 2-phenyl-2-propoxyethanol was replaced with 194 g of 2-butoxy-2-phenylethanol and 540 g of toluene was replaced with 580 g of cyclohexane, to obtain 130.5 g of 2-butoxy-2-phenylethanal (yield: 68%).

Sources & evidence

ORD record
ord-68d9cc76e0184287a214703db6e16b74
Source dataset
uspto-grants-1996_03
Patent number
US05500484

Reaction notes

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