1-(2-Methoxyphenyl)piperazine → 1-{3-[5-Chloro-2-(4-chlorophenyl)-1H-indol-3-yl]-1-oxopropyl}-4-(2-methoxyphenyl)piperazine
Reaction equation
[CH3:23][O:24][c:25]1[c:26]([N:31]2[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]2)[cH:27][cH:28][cH:29][cH:30]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]([CH2:18][CH2:19][C:20](=[O:21])[OH:22])[c:6](-[c:11]3[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]3)[nH:7][c:8]2[cH:9][cH:10]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([CH2:18][CH2:19][C:20](=[O:21])[N:34]3[CH2:33][CH2:32][N:31]([c:26]4[c:25]([O:24][CH3:23])[cH:30][cH:29][cH:28][cH:27]4)[CH2:36][CH2:35]3)[c:6](-[c:11]3[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]3)[nH:7][c:8]2[cH:9][cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-3451cde3d1474833991c1257d6ce8879
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…