反应详情

温度

-33 °C

A solution of 6.0 grams (0.038 mole) of potassium permanganate in about 300 mL of liquid ammonia (-33° C.) is stirred, and 5.3 grams (0.030 mole) of 3-amino-6-bromo-1,2,4-triazine is added portionwise. Upon completion of addition, the reaction mixture is maintained at -33° C. for 15 minutes. Ammonia is then evaporated and the residue is extracted with about 150 mL of hot 1-methylethanol. The solution is concentrated under reduced pressure, yielding 3,5-diamino-6-bromo-1,2,4-triazine.

1. additionUpon completion of addition
2. customAmmonia is then evaporated
3. extractionthe residue is extracted with about 150 mL of hot 1-methylethanol
4. concentrationThe solution is concentrated under reduced pressure