HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane → HCID 86749363, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 86749364 | HCID 86749364 | — |
| Reactant | HCID 86749365 | HCID 86749365 | — |
| Solvent | Cesium carbonate | HCID 10796 | — |
| Product | HCID 86749363 | HCID 86749363 | — |
Reaction Steps
The product of Step 1 above is alkylated with 4-(2-chloroethyl)morphine hydrochloride in dioxane and cesium carbonate. The reaction mixture is concentrated and purified via flash column chromatography to provide the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05502053 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-9daef584d77842579f40fc57f5fc9059 |
| Source note | uspto-grants-1996_03 |