4-Bromopyridine → 4-(Diethylboranyl)pyridine

HRID 1441076Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.C([Li])CCC.[CH2:13]([B:15]([CH2:18][CH3:19])OC)[CH3:14]>>[CH2:13]([B:15]([CH2:18][CH3:19])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1)[CH3:14]

Participants

Reactant 3

HCID 142684-Bromopyridine

HCID 522516Diethylmethoxyborane

HCID 178418339Butyllithium

Product 1

HCID 133188714-(Diethylboranyl)pyridine

Procedure

4-Bromopyridine was reacted with n-butyllithium and then with diethylmethoxyborane using a procedure similar to that in Preparation 49. This gave the title compound, which was used without characterisation.

Sources & evidence

ORD record: ord-3b613c134b5e4b7bbbee9aac7bf6c315
Source dataset: uspto-grants-1996_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05502065

Reaction notes

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