HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dihydroxybutanedioic Acid → Dihydro-3,4-dihydroxy-2,5-furandione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dihydroxybutanedioic Acid | HCID 875 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Dihydro-3,4-dihydroxy-2,5-furandione | HCID 11389406 | — |
Reaction Steps
In the first step, a chiral tartaric anhydride is prepared by reaction of three equivalents of an acid chloride with tartaric acid according to the description in JACS 1933, 55, 2605, and is subsequently reacted with alkenamines at temperatures between 120° C. and 160° C. in suitable inert solvents, such as toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05502206 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-abf970c28a0142faa25ee8e3616e8095 |
| Source note | uspto-grants-1996_03 |