Ammonium → 5-[2-(tetrahydro-pyran-4-ylmethyl)-piperazin-1-yl]-1H-indazole

HRID 144125Notes

Reaction equation

HRID 144125 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH2:23][CH:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[N:11]([c:14]2[cH:15][c:16]3[cH:17][n:18][nH:19][c:20]3[cH:21][cH:22]2)[CH2:12][CH2:13]1.[CH3:34][OH:35].[CH:30]([O-:31])=[O:32].[NH4+:33].[OH-:36].[OH-:37].[Pd+2:38]>>[NH:8]1[CH2:9][CH:10]([CH2:23][CH:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[N:11]([c:14]2[cH:15][c:16]3[cH:17][n:18][nH:19][c:20]3[cH:21][cH:22]2)[CH2:12][CH2:13]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 283FormateHCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 57825833HCID 57825833, compound

Product 1

HCID 497982435-[2-(tetrahydro-pyran-4-ylmethyl)-piperazin-1-yl]-1H-indazole

Sources & evidence

ORD record
ord-67eb2083965548fc959be2d9dccda30e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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