2,5-dichloro-N-(2-((1-methylethyl)sulfonyl)phenyl)-4-pyrimidinamine → 5-Chloro-N(2)-(1,4-diethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl)-N(4)-[2-(propane-2-sulfonyl)-phenyl]-pyrimidine-2,4-diamine
Reaction equation
[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([CH2:15][CH3:16])[CH2:7][c:8]2[c:9]1[cH:10][c:11]([NH2:14])[cH:12][cH:13]2.[Cl:17][c:18]1[n:19][cH:20][c:21]([Cl:37])[c:22]([NH:24][c:25]2[c:26]([S:31](=[O:32])(=[O:33])[CH:34]([CH3:35])[CH3:36])[cH:27][cH:28][cH:29][cH:30]2)[n:23]1>>[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([CH2:15][CH3:16])[CH2:7][c:8]2[c:9]1[cH:10][c:11]([NH:14][c:18]1[n:19][cH:20][c:21]([Cl:37])[c:22]([NH:24][c:25]3[c:26]([S:31](=[O:32])(=[O:33])[CH:34]([CH3:35])[CH3:36])[cH:27][cH:28][cH:29][cH:30]3)[n:23]1)[cH:12][cH:13]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-538cdb7f61f545149992c4d94fad4836
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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