HCID 68686922, compound → HCID 86613528, compound

Participants

Reaction Steps

A solution of 4-(N-butyryl-N-ethylamino)-5-methylisoxazole (Method 10; 45 g, 230 mM) in EtOH (1.5 l) was hydrogenated over 10% Pd/C (11.25 g) at 4 bar. The catalyst was filtered off and the solution was evaporated. The residue was triturated with ether and the crystalline intermediate was filtered off (33.94 g). This was used without further purification.

Provenance & Evidence