反应详情

温度

95 °C

The title compound was prepared from (2R,5S)-1-acetyl-2,5-dimethyl-4-(4-nitrophenyl)piperazine (Method 30, 6.5 g, 26.29 mmol) and cyanamide (2.43 g, 57.84 mmol) by the procedure of Method 31 and heating for 10 h at 95° C. The bicarbonate salt was dried in vac oven at 60° C. overnight. It was obtained as a solid (10.23 g, >100% contaminated with solvent). M/z 290.

1. dry with materialThe bicarbonate salt was dried in vac oven at 60° C. overnight
2. customIt was obtained as a solid (10.23 g, >100% contaminated with solvent)