Potassium Carbonate → HCID 58646872, compound

Participants

Reaction Conditions

Reaction Steps

4-nitro-1-naphthalamine (2.00 g, 10.63 mmol) and citraconic anhydride (1.05 mL, 11.69 mmol) were dissolved in acetic acid (10 mL) and heated to 115° C. for 14 h. The reaction was then cooled to 25° C. and transferred to cold sat K2CO3 with vigorous stirring. After 15 min, the solution was filtered, rinsed with water and dried under vacuum to yield 3.63 g of compound 16A as a yellow solid. This material was taken on to the next step without further purification.

Provenance & Evidence