HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 4-(Piperidin-1-yl)-3-(trifluoromethyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Bromo-3-(trifluoromethyl)benzonitrile | HCID 10800647 | — |
| Product | 4-(Piperidin-1-yl)-3-(trifluoromethyl)benzonitrile | HCID 18542982 | — |
Reaction Steps
The title compound is prepared using an analogous method as described in Example 1.1, utilising 4-bromo-3-(trifluoromethyl)-benzonitrile and piperidine (Fluka, Buchs, Switzerland), with a reaction temperature of 95° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07655669B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-b803681c510642058343088ae57f2a16 |
| Source note | uspto-grants-2010_02 |