HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylimidazole → 4-(2-Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylimidazole | HCID 12749 | — |
| Reactant | 4-Chloro-3-(trifluoromethyl)benzonitrile | HCID 2736474 | — |
| Product | 4-(2-Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzonitrile | HCID 68677937 | — |
Reaction Steps
The title compound is prepared using an analogous method as described in Example 1.1, utilising 4-chloro-3-(trifluoromethyl)-benzonitrile (Lancaster Synthesis GmbH) and 2-methyl-imidazole (Fluka, Buchs, Switzerland), with a reaction temperature of 145° C. for 38 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07655669B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-147df7f93a424152b8f8e11694aed57b |
| Source note | uspto-grants-2010_02 |