4-Chloro-3-(trifluoromethyl)benzonitrile → HCID 68678951, compound

HRID 1441745Notes

Reaction equation

HRID 1441745 reaction equation
Cl[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].[CH3:14][C:15]1[NH:16][CH:17]=[C:18]([CH3:20])[N:19]=1>>[CH3:14][C:15]1[N:16]([C:2]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=2[C:10]([F:13])([F:12])[F:11])[CH:17]=[C:18]([CH3:20])[N:19]=1

Participants

3

Reactant 2

HCID 27364744-Chloro-3-(trifluoromethyl)benzonitrileHCID 178430880HCID 178430880, compound

Product 1

HCID 68678951HCID 68678951, compound

Procedure

The title compound is prepared using an analogous method as described in Example 1.1, utilising 4-chloro-3-(trifluoromethyl)-benzonitrile (Lancaster Synthesis GmbH) and 2,4-dimethyl-imidazole (Trans World Chemicals), with a reaction temperature of 145° C. for 20 hours.

Sources & evidence

ORD record
ord-7a2c764eb9594fb78f316490545d7f13
Source dataset
uspto-grants-2010_02
Patent number
US07655669B2

Reaction notes

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