HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanone → HCID 12862446, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | p-Tolylacetonitrile | HCID 76280 | — |
| Product | HCID 12862446 | HCID 12862446 | 63% |
Reaction Steps
The procedure outlined in example 1 is repeated with cyclohexanone (22.34 g, 0.29 mol), p-tolylacetonitrile (20.96 g, 0.16 mol) and KOH (1.79 g, 0.032 mol). Short path distillation of the crude at 0.05 mbar/115-130° C. followed by recrystallization from hexane yields 21.1 g (63% yield) of product as white crystals, m.p. 50.5-51.3° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07655701B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-963ebf937d3e47398e1370745a449557 |
| Source note | uspto-grants-2010_02 |