1-Octanol → HCID 178443872, compound

Participants

Reaction Steps

In a 250 ml Schlenk flask, 48.04 g (0.381 moles) of dimethyl sulfate was slowly added dropwise to 47.31 g (0.381 moles) of butylimidazole with ice cooling and under a blanket gas. Stirring of the mixture was continued at room temperature over night. After the addition of 62.72 g (0.482 moles; 1.26 equ.) of 1-octanol and 0.67 g of Dowex ion-exchanger washed with acetone and dried under high vacuum, the mixture was allowed to react over night at 140° C., and at the same time, the by-product methanol formed was removed from the reaction mixture by sparging with an argon stream. The remaining volatile fractions were subsequently removed under high vacuum at 80° C. The product, 1-butyl-3-methylimidazolium 1-octyl sulfate, was obtained as a viscous, slightly yellow liquid in quantitative yield. The product does not contain any detectable amounts of Cl− contamination (AgNO3 test; <3 ppm).

Provenance & Evidence