HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,5-Trifluorobenzaldehyde → 2-[Bis(cyclopropylmethyl)amino]-3,5-difluorobenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,5-Trifluorobenzaldehyde | HCID 2776950 | — |
| Reactant | Bis(cyclopropylmethyl)amine | HCID 15284719 | — |
| Reactant | N-(cyclopentylmethyl)-N-ethylamine | HCID 43163716 | — |
| Product | 2-[Bis(cyclopropylmethyl)amino]-3,5-difluorobenzaldehyde | HCID 86628977 | — |
Reaction Steps
By using 2,3,5-trifluorobenzaldehyde instead of 2-fluoro-5-(trifluoromethyl)benzaldehyde, and N,N-bis(cyclopropylmethyl)amine synthesized by the method described in International Patent Publication WO2006/073973 instead of N-(cyclopentylmethyl)-N-ethylamine, reactions and treatments were performed in the same manner as those of Step 3 of Example 1 to obtain 2-[bis(cyclopropylmethyl)amino]-3,5-difluorobenzaldehyde as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659271B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-1c44551e5365410ba8aadd71b3bf484e |
| Source note | uspto-grants-2010_02 |