HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 58610101, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| Reactant | 3-Bromobenzonitrile | HCID 23381 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 58610101 | HCID 58610101 | 21% |
Reaction Steps
A mixture of 3-bromobenzonitrile (2.00 g, 11 mmol), methyl thiosalicylate (2.87 g, 17 mmol), triethylamine (1.95 g, 19 mmol) and toluene (10 ml) was heated and refluxed under a nitrogen flow for 40 hours. The precipitated crystals were taken by filtration and recrystallized from tetrahydrofuran-ethyl acetate to give the title compound (0.72 g, 21%) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659267B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-e6c540d3c96e4af6a8318a42ed6f33c8 |
| Source note | uspto-grants-2010_02 |