HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 136045163, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| Reactant | p-Cyanophenyl acetate | HCID 83062 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 136045163 | HCID 136045163 | 16% |
Reaction Steps
A mixture of 4-acetoxybenzonitrile (1.35 g, 8.4 mmol), methyl thiosalicylate (2.12 g, 13 mmol), triethylamine (1.50 g, 15 mmol) and toluene (10 ml) was heated and refluxed under a nitrogen flow for 26 hours. The precipitated crystals were taken by filtration and recrystallized from tetrahydrofuran-ethyl acetate to give the title compound (0.34 g, 16%) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659267B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-d177a1fea6eb4cf5b1fb504c1d9a5e08 |
| Source note | uspto-grants-2010_02 |