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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 144267Generated: October 25, 2026

o-Xylyl bromide → 2,2-Dimethyl-3-{2-[3-[2-(2-methyl-benzyloxy)-ethyl]-3-(trans-4-methyl-cyclohexyl)ureido]-thiazol-5-ylsulfanyl}-propionic acid

https://huagongshe.com/reaction/144267

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-Xylyl bromideHCID 6992—
Reactant3-{2-[3-[2-(2-Chloro-benzyloxy)-ethyl]-3-(trans-4-methylcyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2,2-dimethyl-propionic acidHCID 24987101—
Reactant3-(2-Amino-thiazol-5-ylsulfanyl)-2,2-dimethyl-propionic acid ethyl esterHCID 57481429—
Product2,2-Dimethyl-3-{2-[3-[2-(2-methyl-benzyloxy)-ethyl]-3-(trans-4-methyl-cyclohexyl)ureido]-thiazol-5-ylsulfanyl}-propionic acidHCID 24989308—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-45e21241a34948ba9a122614ecdd31cf
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)