HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → HCID 11605095, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Dimethylamine, hydrochloride | HCID 10473 | — |
| Reactant | HCID 11597308 | HCID 11597308 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 11605095 | HCID 11605095 | 50.2% |
Reaction Steps
2-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzooxazole-5-carboxylic acid (150 mg, 0.343 mmol), DMAP (125 mg, 1.03 mmol), EDC (99 mg, 0.514 mmol), and dimethylamine hydrochloride (42 mg, 0.514 mmol) are reacted analogous to Example 3 to give the title product (80 mg, 50%). MS (ES) m/e: 465.3 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659296B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-9db57754d54d476ea79e2d6b7889f612 |
| Source note | uspto-grants-2010_02 |