1,2-Dichloroethane → HCID 11518859, compound

Participants

Reaction Steps

2-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzooxazole-5-carboxylic acid (150 mg, 0.343 mmol), DMAP (125 mg, 1.03 mmol), EDC (99 mg, 0.514 mmol), and glycine methyl ester hydrochloride (64 mg, 0.514 mmol) are reacted and hydrolyzed analogous to Example 4 to give the title product (130 mg, 76%). MS (ES) m/e: 495.3 (M+1), 493.3 (M−1).

Provenance & Evidence