Acetic Acid → 8-{[3-(5,7-difluoro-1H-indol-3-yl)propyl]amino}-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one
Reaction equation
[C:35]([BH3-:36])#[N:37].[CH3:31][C:32](=[O:33])[OH:34].[CH3:39][OH:40].[F:16][c:17]1[cH:18][c:19]2[c:20]([CH2:27][CH2:28][CH:29]=[O:30])[cH:21][nH:22][c:23]2[c:24]([F:26])[cH:25]1.[NH2:1][CH:2]1[CH2:3][c:4]2[c:5]3[c:9]([cH:10][cH:11][c:12]2[O:13][CH2:14]1)[CH2:8][NH:7][C:6]3=[O:15].[Na+:38]>>[NH:1]([CH:2]1[CH2:3][c:4]2[c:5]3[c:9]([cH:10][cH:11][c:12]2[O:13][CH2:14]1)[CH2:8][NH:7][C:6]3=[O:15])[CH2:29][CH2:28][CH2:27][c:20]1[c:19]2[cH:18][c:17]([F:16])[cH:25][c:24]([F:26])[c:23]2[nH:22][cH:21]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a894c862fa184b6c9bc9452951706500
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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