2-Amino-4-methylthiazole → [7-(5-Fluoro-pyridin-3-yl)-2-methyl-thiazolo[4,5-c]pyridin-4-yl]-(4-methyl-thiazol-2-yl)-amine

Participants

Role	Name	HCID	Charge
Reactant	2-Amino-4-methylthiazole	HCID 74143	—
Reactant	(5-Fluoropyridin-3-yl)boronic acid	HCID 44717403	—
Reactant	4-Chloro-7-iodo-2-methylthiazolo[4,5-c]pyridine	HCID 76850478	—
Product	[7-(5-Fluoro-pyridin-3-yl)-2-methyl-thiazolo[4,5-c]pyridin-4-yl]-(4-methyl-thiazol-2-yl)-amine	HCID 16660899	—

Reaction Steps

The title compound, MS: m/e=358.2 (M+H+), was prepared in accordance with the general method of example 2, step 1 and step 2 from 4-chloro-7-iodo-2-methyl-thiazolo[4,5-c]pyridine (Example B), 3-fluoro-5-pyridineboronic acid and 2-amino-4-methylthiazole.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07659401B2
Source dataset	uspto-grants-2010_02
ORD ID	ord-f0fd15340bb149d8867f0a2ba3dc6b90
Source note	uspto-grants-2010_02