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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1443093Generated: November 1, 2026

2-Methyl-1,3-thiazol-4-amine → HCID 16660901, compound

https://huagongshe.com/reaction/1443093

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-1,3-thiazol-4-amineHCID 14772700—
Reactant(5-Fluoropyridin-3-yl)boronic acidHCID 44717403—
Reactant4-Chloro-7-iodo-2-methylthiazolo[4,5-c]pyridineHCID 76850478—
ProductHCID 16660901HCID 16660901—

Reaction Steps

The title compound, MS: m/e=358.2 (M+H+), was prepared in accordance with the general method of example 2, step 1 and step 2 from 4-chloro-7-iodo-2-methyl-thiazolo[4,5-c]pyridine (Example B), 3-fluoro-5-pyridineboronic acid and 4-amino-2-methylthiazole (Example C).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07659401B2
Source datasetuspto-grants-2010_02
ORD IDord-cc101b9a4f3a47bbb421d2be85f94840
Source noteuspto-grants-2010_02