HRID1443124

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID222

Ammonia gas

H3N

HCID10012760

5-nitro-1H-isochromen-1-one

C9H5NO4

PRODUCTS

生成物

HCID231378

5-nitro-1(2H)-isoquinolinone

C9H6N2O3

收率 79.7%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

2.51 g (13.13 mmol) of 5-nitroisocoumarin is added in 100 ml of ethanol. Ammonia is pressure-forced in in an autoclave. The product precipitates and is suctioned off. 1.98 g (79.7%) of the desired compound is isolated.

WORKUP

后处理

customThe product precipitates