HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyquinolin-5-amine → 1,1,1-Trifluoro-4-phenyl-2-[(2-methoxyquinolin-5-yl)iminomethyl]-4-methylpentan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyquinolin-5-amine | HCID 12283036 | — |
| Reactant | 2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethylpentanal | HCID 17989092 | — |
| Product | 1,1,1-Trifluoro-4-phenyl-2-[(2-methoxyquinolin-5-yl)iminomethyl]-4-methylpentan-2-ol | HCID 17989263 | — |
Reaction Steps
Analogously to Example 13, 200 mg of 2-hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)pentanal and 122 mg of 5-amino-2-methoxyquinoline are converted into 190 mg of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659297B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-3493ae2510ab44938076d68041f2eaae |
| Source note | uspto-grants-2010_02 |