HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-2-(trifluoromethyl)benzonitrile → 1,1,1-Trifluoro-4-phenyl-2-[(4-cyano-3-(trifluoromethyl)phenyl)iminomethyl]-4-methylpentan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-2-(trifluoromethyl)benzonitrile | HCID 522170 | — |
| Reactant | 2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethylpentanal | HCID 17989092 | — |
| Product | 1,1,1-Trifluoro-4-phenyl-2-[(4-cyano-3-(trifluoromethyl)phenyl)iminomethyl]-4-methylpentan-2-ol | HCID 17989176 | — |
Reaction Steps
Analogously to Example 13, 120 mg of 2-hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)pentanal and 78 mg of 4-cyano-3-(trifluoromethyl)aniline are converted into 71 mg of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659297B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-0c63a85fca824585afd1173504a75f85 |
| Source note | uspto-grants-2010_02 |