HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1(2H)-phthalazinone → HCID 68679773, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1(2H)-phthalazinone | HCID 12341002 | — |
| Reactant | 4-(3-Fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanal | HCID 17989086 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Product | HCID 68679773 | HCID 68679773 | 12.3% |
Reaction Steps
Analogously to Example 10, the corresponding imine is produced starting from 200 mg of 4-(3-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)-pentanal and 105 mg of 5-amino-phthalazin-1-one. As in Example 3, 50 mg of imine is reacted by reaction with 0.22 ml of titanium tetrachloride, and 36 mg of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659297B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-c493e36f1838416b9fc56a824dd6d425 |
| Source note | uspto-grants-2010_02 |