HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 17989133, compound → HCID 17989219, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 17989133 | HCID 17989133 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 17989219 | HCID 17989219 | 89.9% |
Reaction Steps
2.78 g (9.78 mmol) of ethyl-4-(4-fluoro-3-methoxyphenyl)-2-hydroxy-4-methylpentanoate is oxidized to the corresponding α-ketoester with SO3/Py in dichloromethane as in Example 273. After chromatography on a Flashmaster, 2.48 g (89.9%) of the desired compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659297B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-f7068cf7fb59455fb7582746d7a52574 |
| Source note | uspto-grants-2010_02 |