Dichloromethane → ethyl 2-[3-fluoro-4-(N-thiazol-2-ylamino)phenyl]propionate
Reaction equation
[Br:16][c:17]1[s:18][cH:19][cH:20][n:21]1.[CH2:22]([Cl:23])[Cl:24].[F:1][c:2]1[cH:3][c:4]([CH:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH3:15])[cH:5][cH:6][c:7]1[NH2:8]>>[F:1][c:2]1[cH:3][c:4]([CH:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH3:15])[cH:5][cH:6][c:7]1[NH:8][c:17]1[s:18][cH:19][cH:20][n:21]1Participants
4
Sources & evidence
- ORD record
- ord-04a98e4ba03c4819aef89078510a0abd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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