4-Methoxy-2-nitrobenzene-1-carboximidic acid → 2-Amino-4-methoxybenzamide

Participants

Reaction Steps

A suspension of 4-methoxy-2-nitro-benzamide (6.9 g, 35.1 mmol) in EtOH (200 ml) was hydrogenated with Raney-Ni (4.0 g) for two days at room temperature and 50 psi. The catalyst was filtered of and washed with DMF. The solvent was evaporated under reduced pressure. Yield: 5.6 g, 95%.

Provenance & Evidence