HuagongsheHuagongshe Chemistry Print Report · For research reference only
17-Hydroxy-13-methyl-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0*4,6*]octadec-7-ene-4-carboxylic acid ethyl ester → HCID 68685016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 17-Hydroxy-13-methyl-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0*4,6*]octadec-7-ene-4-carboxylic acid ethyl ester | HCID 68410372 | — |
| Reactant | HCID 178487728 | HCID 178487728 | — |
| Product | HCID 68685016 | HCID 68685016 | 17% |
Reaction Steps
Quinazolinol derivative (83) (449 mg, 1.7 mmol) was coupled to compound 51 (400 mg, 1.1 mmol) followed by hydrolysis of the ethyl ester as described in example 52, which gave the title compound (112 mg, 17%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659245B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-2ac69455665e4bb0beed407f30add1c5 |
| Source note | uspto-grants-2010_02 |