Sulfuric Acid → HCID 57687185, compound

HRID 1443469Notes

Reaction equation

HRID 1443469 reaction equation
[CH3:1][O:2][C:3]1[C:10]([CH3:11])=[CH:9][C:6]([C:7]#[N:8])=[C:5]([N+:12]([O-:14])=[O:13])[CH:4]=1.S(=O)(=O)(O)[OH:16]>O>[CH3:1][O:2][C:3]1[C:10]([CH3:11])=[CH:9][C:6]([C:7]([NH2:8])=[O:16])=[C:5]([N+:12]([O-:14])=[O:13])[CH:4]=1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 57687200HCID 57687200, compound

Product 1

HCID 57687185HCID 57687185, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
105 °C

Procedure

To a mixture of 4-methoxy-5-methyl-2-nitro-benzonitrile (8 g, 40 mmol) and water (50 ml) was added concentrated sulphuric acid (65 ml) and the mixture was stirred for 2.5 hours at 100-110° C. The mixture was allowed to stay overnight, filtered, washed with water and dried which gave the title compound (7 g, 83%).

Workup

  1. waitto stay overnight
  2. filtrationfiltered
  3. washwashed with water
  4. customdried which

Sources & evidence

ORD record
ord-3107a1133fc84decbc670a2f2f931734
Source dataset
uspto-grants-2010_02
Patent number
US07659245B2

Reaction notes

Loading…