HCID 57687185, compound → HCID 59165434, compound

Participants

Reaction Steps

Compound 110 (7.0 g, 33.3 mmol) was hydrogenated in EtOH (200 ml) and raney-ni (5.0 g) overnight at room temperature at 50 psi. The catalyst was filtered off and washed with dioxane and ethanol. The solvent was removed under vacuo and the product was isolated by column chromatography on silica gel eluted with dichloromethane and 3% methanol. Yield: 3.4 g=56%.

Provenance & Evidence