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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1443500Generated: October 29, 2026

Cyclopropanesulfonamide → N-[17-[2-Ethoxy-7-methoxy-8-methylquinazolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carbonyl](cyclopropyl)sulfonamide

https://huagongshe.com/reaction/1443500

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanesulfonamideHCID 15765418—
Reactant17-[2-Ethoxy-7-methoxy-8-methylquinazolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carboxylic acidHCID 68409293—
ProductN-[17-[2-Ethoxy-7-methoxy-8-methylquinazolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carbonyl](cyclopropyl)sulfonamideHCID 68689567—

Reaction Steps

The acid (149) was reacted with cyclopropylsulfonamide according to the procedure described in example 147, which gave the title compound, m/z=670 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07659245B2
Source datasetuspto-grants-2010_02
ORD IDord-a4c4aacad3f740d8b1e8ee93de687aeb
Source noteuspto-grants-2010_02