Phenyl isocyanate → N-[4-(1,4-Diazabicyclo[3.2.2]non-4-yl)phenyl]-N′-phenylurea

Participants

Reaction Steps

A mixture of 4-(1,4-diaza-bicyclo[3.2.2]non-4-yl)-phenylamine (0.43 g, 2.0 mmol), phenylisocyanate (0.29 ml, 2.5 mmol) and methanol (60 ml) was stirred at room temperature for 40 hours. The mixture was evaporated and diethylether (30 ml) was added, the precipitate was filtered. The product was isolated. Yield 0.23 g (34%). Mp. 145° C. (dec).

Provenance & Evidence