Hydrochloric Acid → HCID 68410208, compound

Participants

Reaction Steps

A stream of dry hydrogen chloride was passed through a mixture of 2-amino-5-cyano-4-methylthiophene-3-carboxylic acid ethyl ester (0.003 mol) and benzonitrile (0.0045 mol) in 20 ml. of dioxane for 2 hours. Then, the reaction was stirred at room temperature for 12 hours, subsequently, the solvent was removed under reduced pressure and the residue was triturated with diethyl ether. A precipitate was obtained, filtered and dried to yield (92% yield) the title compound as a brown solid.

Provenance & Evidence