N-(4-ethynylphenyl)acetamide → HCID 11602957, compound

HRID 1443786Notes

Reaction equation

HRID 1443786 reaction equation
Br[C:2]1[N:7]=[N:6][C:5]([N:8]2[CH2:14][CH:13]3[N:15]([CH3:16])[CH:10]([CH2:11][CH2:12]3)[CH2:9]2)=[CH:4][CH:3]=1.[C:17]([C:19]1[CH:24]=[CH:23][C:22]([NH:25][C:26](=[O:28])[CH3:27])=[CH:21][CH:20]=1)#[CH:18]>>[CH3:16][N:15]1[CH:13]2[CH2:12][CH2:11][CH:10]1[CH2:9][N:8]([C:5]1[N:6]=[N:7][C:2]([C:18]#[C:17][C:19]3[CH:24]=[CH:23][C:22]([NH:25][C:26](=[O:28])[CH3:27])=[CH:21][CH:20]=3)=[CH:3][CH:4]=1)[CH2:14]2

Participants

3

Reactant 2

HCID 11412536N-(4-ethynylphenyl)acetamideHCID 86239615HCID 86239615, compound

Product 1

HCID 11602957HCID 11602957, compound

Procedure

Was prepared according to Method B from 3-(6-bromo-pyridazin-3-yl)-8-methyl-3,8-diaza-bicyclo[3.2.1]octane and N-(4-ethynyl-phenyl)-acetamide. Mp 292° C.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-d8df36b265ae44eba9c08d681e3c21d4
Source dataset
uspto-grants-2010_02
Patent number
US07662812B2

Reaction notes

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