Ethyl isocyanate → HCID 11710863, compound

HRID 1443792Notes

Reaction equation

HRID 1443792 reaction equation
[CH3:1][N:2]1[CH:7]2[CH2:8][CH2:9][CH:3]1[CH2:4][N:5]([C:10]1[N:15]=[N:14][C:13]([C:16]#[C:17][C:18]3[CH:23]=[CH:22][C:21]([NH2:24])=[CH:20][CH:19]=3)=[CH:12][CH:11]=1)[CH2:6]2.[CH2:25]([N:27]=[C:28]=[O:29])[CH3:26]>>[CH2:25]([NH:27][C:28]([NH:24][C:21]1[CH:20]=[CH:19][C:18]([C:17]#[C:16][C:13]2[N:14]=[N:15][C:10]([N:5]3[CH2:6][CH:7]4[N:2]([CH3:1])[CH:3]([CH2:9][CH2:8]4)[CH2:4]3)=[CH:11][CH:12]=2)=[CH:23][CH:22]=1)=[O:29])[CH3:26]

Participants

3

Reactant 2

HCID 8022Ethyl isocyanateHCID 11709521HCID 11709521, compound

Product 1

HCID 11710863HCID 11710863, compound

Procedure

Was prepared according to Method F from 4-[6-(8-methyl-3,8-diaza-bicyclo[3.2.1]oct-3-yl)-pyridazin-3-ylethynyl]-phenylamine and ethylisocyanate. Mp 269° C. LC-ESI-HRMS of [M+H]+ shows 391.2253 Da. Calc. 391.224634 Da, dev. 1.7 ppm.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-f8313148f68940f6b46e86ba9ee747b1
Source dataset
uspto-grants-2010_02
Patent number
US07662812B2

Reaction notes

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