Ethyl 7-chloropyrazolo[1,5-a]pyrimidine-5-carboxylate → 2-Phenyl-7-chloro-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester

HRID 1443843Notes

Reaction equation

HRID 1443843 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[NH:7][C:8]2[N:9]([N:13]=[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:15]=2)[C:10](=O)[CH:11]=1)=[O:5])[CH3:2].C(OC(C1C=C([Cl:33])N2N=CC=C2N=1)=O)C>>[CH2:1]([O:3][C:4]([C:6]1[CH:11]=[C:10]([Cl:33])[N:9]2[N:13]=[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:15]=[C:8]2[N:7]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 12366074Ethyl 7-chloropyrazolo[1,5-a]pyrimidine-5-carboxylateHCID 178469339HCID 178469339, compound

Product 1

HCID 586284132-Phenyl-7-chloro-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester

Procedure

This compound was synthesized from 7-oxo-2-phenyl-4,7-dihydro-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester, according to the process for synthesizing 7-chloropyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester. mp: 135-137° C.

Sources & evidence

ORD record
ord-a33b31cc494b4cfca8b37d2263ba6fda
Source dataset
uspto-grants-2010_02
Patent number
US07662826B2

Reaction notes

Loading…