2-Phenyl-7-chloro-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester → 2-Phenyl-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid

HRID 1443845Notes

Reaction equation

HRID 1443845 reaction equation
C([O:3][C:4]([C:6]1[CH:11]=[C:10](Cl)[N:9]2[N:13]=[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH:15]=[C:8]2[N:7]=1)=[O:5])C.C(OC(C1C=CN2N=CC(C3C=CC=C(Cl)C=3)=C2N=1)=O)C>>[C:16]1([C:14]2[CH:15]=[C:8]3[N:7]=[C:6]([C:4]([OH:5])=[O:3])[CH:11]=[CH:10][N:9]3[N:13]=2)[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 586284132-Phenyl-7-chloro-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl esterHCID 586288723-(3-Chlorophenyl)-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester

Product 1

HCID 586283942-Phenyl-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid

Procedure

This compound was synthesized from 2-phenyl-7-chloro-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester, according to the process for synthesizing the foregoing 3-(3-chlorophenyl)-pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester.

Sources & evidence

ORD record
ord-b4239e25c5ea4e91b79618ffc7513ae5
Source dataset
uspto-grants-2010_02
Patent number
US07662826B2

Reaction notes

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