Ethyl pyrazolo[1,5-a]pyrimidine-5-carboxylate → Ethyl 3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate

HRID 1443848Notes

Reaction equation

HRID 1443848 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[N:10]([N:13]=[CH:14][C:15]=2[C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[CH:17]=2)[C:11]=1Cl)=[O:5])[CH3:2].C(OC(C1C=CN2N=CC=C2N=1)=O)C>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[N:10]([N:13]=[CH:14][C:15]=2[C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[CH:17]=2)[CH:11]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 49763022Ethyl pyrazolo[1,5-a]pyrimidine-5-carboxylateHCID 586289053-(3-Chlorophenyl)-7-chloro-pyrazolo-[1,5-a]-pyrimidine-6-carboxylic acid ethyl ester

Product 1

HCID 58628282Ethyl 3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate

Procedure

This compound was synthesized from 3-(3-chlorophenyl)-7-chloro-pyrazolo-[1,5-a]-pyrimidine-6-carboxylic acid ethyl ester, according to the process for synthesizing the foregoing pyrazolo-[1,5-a]-pyrimidine-5-carboxylic acid ethyl ester. mp: 135.5° C.

Sources & evidence

ORD record
ord-b89e632909c040689dcd50bf5f59f04f
Source dataset
uspto-grants-2010_02
Patent number
US07662826B2

Reaction notes

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