HCID 44248848, compound → HCID 44248849, compound

Participants

Reaction Steps

A mixture of 2-nitro-5,6,9,10,11,12-hexahydro-4H,8H-cyclohepta[4,5]pyrrolo[3,2,1-ij]quinoline (0.30 g, 11 mmol) and 5% palladium on carbon (0.10 g) in ethanol (35 mL) was shaken on a Parr hydrogenator under an atmosphere of hydrogen (45 PSI) for 48 h. The reaction mixture was filtered through Celite® and the filter bed was washed with ethanol. The filtrate was concentrated to provide 0.27 g of 5,6,9,10,11,12-hexahydro-4H,8H-cyclohepta[4,5]pyrrolo[3,2,1-ij]quinolin-2-amine.

Provenance & Evidence