HCID 59168385, compound → HCID 59168382, compound

HRID 1443911Notes

Reaction equation

HRID 1443911 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:10]3=[C:11]([CH2:13][CH2:14][N:9]3[C:8]3[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:7]2=3)[CH:12]=1)([O-])=O>[Pd]>[CH:5]1[C:4]([NH2:1])=[CH:12][C:11]2[CH2:13][CH2:14][N:9]3[C:10]=2[C:6]=1[C:7]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][C:8]=13

Participants

3

Reactant 1

HCID 59168385HCID 59168385, compound

Product 1

HCID 59168382HCID 59168382, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Following the procedure of Example 1, step 3, 2-nitro-4,5,8,9,10,11-hexahydro-7H-cyclohepta[b]pyrrolo[3,2,1-hi]indole was hydrogenated over 5% palladium on carbon to provide 4,5,8,9,10,11-hexahydro-7H-cyclohepta[b]pyrrolo[3,2,1-hi]indole-2-amine which was used for the coupling reactions.

Sources & evidence

ORD record
ord-97b75cb54136455982759b2d1dac6814
Source dataset
uspto-grants-2010_02
Patent number
US07662831B2

Reaction notes

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