Potassium Nitrate → HCID 59168389, compound

HRID 1443928Notes

Reaction equation

HRID 1443928 reaction equation
[CH:1]1[CH:9]=[CH:8][C:7]2[CH2:10][CH2:11][N:5]3[C:6]=2[C:2]=1[C:3]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][C:4]=13.[N+:18]([O-])([O-:20])=[O:19].[K+]>S(=O)(=O)(O)O>[N+:18]([C:9]1[CH:1]=[C:2]2[C:6]3=[C:7]([CH2:10][CH2:11][N:5]3[C:4]3[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:3]2=3)[CH:8]=1)([O-:20])=[O:19]

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 13464813HCID 13464813, compound

Product 1

HCID 59168389HCID 59168389, compoundYield 79.3%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Following the procedure of Example 1 Step 2, 4,5,7,8,9,10,11,12-octahydrocycloocta[b]pyrrolo[3,2,1-hi]indole (3.2 g, 14 mmol), potassium nitrate (1.5 g, 14 mmol) and concentrated sulfuric acid (50 mL) provided 2-nitro-4,5,7,8,9,10,11,12-octahydrocycloocta[b]pyrrolo[3,2,1-hi]indole (3.0 g). MS (ES) m/z 271.2; HRMS: calcd for C16H18N2O2+H+, 271.14410; found (ESI, [M+H]+), 271.1437.

Sources & evidence

ORD record
ord-7282533846b84345b3a86fabf7fb9a29
Source dataset
uspto-grants-2010_02
Patent number
US07662831B2

Reaction notes

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