反应详情

Following the procedure of Example 1, Step 3, 2-nitro-4,5,7,8,9,10,11,12-octahydrocycloocta[b]pyrrolo[3,2,1-hi]indole (2.0 g, 7.4 mmol) and 5% palladium on carbon (0.25 g) in ethanol (25 mL) was hydrogenated to provide 4,5,7,8,9,10,11,12-octahydrocycloocta[b]pyrrolo[3,2,1-hi]indol-2-amine. MS (ES) m/z 241.2; HRMS: calcd for C16H20N2+H+, 241.16992; found (ESI, [M+H]+), 241.1693.