HCID 59168383, compound → HCID 59168384, compound

HRID 1443934Notes

Reaction equation

HRID 1443934 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:11]3=[C:12]([C:14]4[CH2:20][CH2:19][CH2:18][CH2:17][C:16](=[O:21])[C:15]=4[N:10]3[CH2:9][CH2:8][CH2:7]2)[CH:13]=1)([O-])=O>[Pd].C(O)C>[O:21]=[C:16]1[C:15]2[N:10]3[C:11]4[C:6](=[CH:5][C:4]([NH2:1])=[CH:13][C:12]=4[C:14]=2[CH2:20][CH2:19][CH2:18][CH2:17]1)[CH2:7][CH2:8][CH2:9]3

Participants

4

Reactant 1

HCID 59168383HCID 59168383, compound

Product 1

HCID 59168384HCID 59168384, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Following the procedure of Example 1, Step 3, 2-nitro-8-oxo-5,6,9,10,11,12-hexahydro-4H,8H-cyclohepta[4,5]pyrrolo[3,2,1-ij]quinoline (0.10 g, 0.37 mmol) and 5% palladium on carbon (30 mg) in ethanol (25 mL) was hydrogenated to provide 8-oxo-5,6,9,10,11,12-hexahydro-4H,8H-cyclohepta[4,5]pyrrolo[3,2,1-ij]quinolin-2-amine.

Sources & evidence

ORD record
ord-d8cb806968414f20b3e308fea47f5f77
Source dataset
uspto-grants-2010_02
Patent number
US07662831B2

Reaction notes

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