3-Pyridinemethanol → HCID 59168160, compound

HRID 1444008Notes

Reaction equation

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][OH:8])[CH:2]=1.Br[C:10]1[N:11]=[CH:12][C:13]([NH:17][S:18]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([Cl:27])[C:22]=2[Cl:28])(=[O:20])=[O:19])=[N:14][C:15]=1[Cl:16]>>[Cl:28][C:22]1[C:23]([Cl:27])=[CH:24][CH:25]=[CH:26][C:21]=1[S:18]([NH:17][C:13]1[C:12]([O:8][CH2:7][C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)=[N:11][CH:10]=[C:15]([Cl:16])[N:14]=1)(=[O:20])=[O:19]

Participants

Reactant 2

HCID 75103-Pyridinemethanol

HCID 10126995HCID 10126995, compound

Product 1

HCID 59168160HCID 59168160, compound

Procedure

Prepared by the method of Example 31 using pyridine-3-methanol (0.22 g) and N-(3-bromo-6-chloro-2-pyrazinyl)-2,3-dichlorobenzenesulphonamide (Example 98) (0.2 g).

Sources & evidence

ORD record: ord-8184ac89c60642bc96fa18d0d6e77bf7
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07662825B2

Reaction notes

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